Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
Identifieur interne : 000660 ( Main/Exploration ); précédent : 000659; suivant : 000661Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines
Auteurs : V J Lund [Royaume-Uni] ; P M Clarke [Royaume-Uni] ; A C Swift [Royaume-Uni] ; G W Mcgarry [Royaume-Uni] ; C. Kerawala [Royaume-Uni] ; D. Carnell [Royaume-Uni]Source :
- The Journal of Laryngology and Otology [ 0022-2151 ] ; 2016.
Abstract
This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. With only limited high-level evidence for management of nasal and paranasal sinus cancers owing to low incidence and diverse histology, this paper provides recommendations on the work up and management based on the existing evidence base.
• Sinonasal tumours are best treated
• Treatment of sinonasal malignancy should be carefully planned and discussed at a specialist skull base multidisciplinary team meeting with all relevant expertise. (G)
• Complete surgical resection is the mainstay of treatment for inverted papilloma and juvenile angiofibroma. (R)
• Essential equipment is necessary and must be available prior to commencing endonasal resection of skull base malignancy. (G)
• Endoscopic skull base surgery may be facilitated by two surgeons working simultaneously, utilising both sides of the nose. (G)
• To ensure the optimum oncological results, the primary tumour must be completely removed and margins checked by frozen section if necessary. (G)
• The most common management approach is surgery followed by post-operative radiotherapy, ideally within six weeks. (R)
• Radiation is given first if a response to radiation may lead to organ preservation. (G)
• Radiotherapy should be delivered within an accredited department using megavoltage photons from a linear accelerator (typical energies 4–6 MV) as an unbroken course. (R)
Url:
DOI: 10.1017/S0022215116000530
PubMed: 27841122
PubMed Central: 4873911
Affiliations:
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Kerawala</name><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>The Royal Marsden Hospital</institution>,<addr-line>London</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Carnell, D" sort="Carnell, D" uniqKey="Carnell D" first="D" last="Carnell">D. Carnell</name><affiliation wicri:level="1"><nlm:aff id="aff6"><addr-line>Department of Oncology</addr-line>,<institution>University College Hospital</institution>,<addr-line>London</addr-line>,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">The Journal of Laryngology and Otology</title><idno type="ISSN">0022-2151</idno><idno type="eISSN">1748-5460</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. With only limited high-level evidence for management of nasal and paranasal sinus cancers owing to low incidence and diverse histology, this paper provides recommendations on the work up and management based on the existing evidence base.</p><sec id="sec_a1"><title>Recommendations</title><p>• Sinonasal tumours are best treated <italic>de novo</italic> and unusual polyps should be imaged and biopsied prior to definitive surgery. (G)</p><p>• Treatment of sinonasal malignancy should be carefully planned and discussed at a specialist skull base multidisciplinary team meeting with all relevant expertise. (G)</p><p>• Complete surgical resection is the mainstay of treatment for inverted papilloma and juvenile angiofibroma. (R)</p><p>• Essential equipment is necessary and must be available prior to commencing endonasal resection of skull base malignancy. (G)</p><p>• Endoscopic skull base surgery may be facilitated by two surgeons working simultaneously, utilising both sides of the nose. (G)</p><p>• To ensure the optimum oncological results, the primary tumour must be completely removed and margins checked by frozen section if necessary. (G)</p><p>• The most common management approach is surgery followed by post-operative radiotherapy, ideally within six weeks. (R)</p><p>• Radiation is given first if a response to radiation may lead to organ preservation. (G)</p><p>• Radiotherapy should be delivered within an accredited department using megavoltage photons from a linear accelerator (typical energies 4–6 MV) as an unbroken course. (R)</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Lund, Vj" uniqKey="Lund V">VJ Lund</name></author><author><name sortKey="Howard, D" uniqKey="Howard D">D Howard</name></author><author><name sortKey="Wei, W" uniqKey="Wei W">W. Wei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Edge, Sb" uniqKey="Edge S">SB Edge</name></author><author><name sortKey="Compton, Cc" uniqKey="Compton C">CC Compton</name></author><author><name sortKey="Fritz, Ag" uniqKey="Fritz A">AG Fritz</name></author><author><name sortKey="Greene, Fl" uniqKey="Greene F">FL Greene</name></author><author><name sortKey="Trotti, A" uniqKey="Trotti A">A. 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Kerawala</name><name sortKey="Mcgarry, G W" sort="Mcgarry, G W" uniqKey="Mcgarry G" first="G W" last="Mcgarry">G W Mcgarry</name><name sortKey="Swift, A C" sort="Swift, A C" uniqKey="Swift A" first="A C" last="Swift">A C Swift</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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